Although we demonstrated here that JMJD3 inhibition aggravates renal fibroblast activation and renal fibrosis in the kidney after nephrectomy and UUO injury, a recent report indicates that inhibition of JMJD3 attenuated podocyte injury and glomerular disease in models of nephrotoxicity and diabetes 38. This evidence concerns the gene KDM6B and glomerular disorder.