Furthermore, there was an increase in the Tregs subset (CD3+CD45+CD4+CD25+Foxp3+) in the cisplatin (∗∗∗P < 0.001 vs. T), moxibustion (∗∗P < 0.01 vs. T), and combinatorial therapy (∗∗P < 0.01 vs. T) groups compared with that in the untreated tumor-bearing mice. This evidence concerns the gene CD4 and neoplasm.