On the other hand, Yoo et al. found that the SLC1A5 variant is a mitochondrial glutamine transporter used for metabolic reprogramming of pancreatic cancer, and the knockout or overexpression of the SLC1A5 variant alters the growth of cancer cells and tumors, thus, supporting carcinogenesis [13]. Here, SLC1A5 is linked to familial pancreatic carcinoma.