KEGG analysis of target genes mainly enriched in JAK-STAT signaling pathway, human T-cell leukemia virus 1 infection, apelin signaling pathway, and hepatitis B. Aberrant signaling pathways were crucial for the tumorigenesis and increasing evidence indicated that JAK-STAT pathway was involved in the development of HCC 53. This evidence concerns the gene SOAT1 and hepatocellular carcinoma.