According to the tumor locations, MRPL27 mRNA was significantly overexpression in tumor tissues in intrahepatic cholangiocarcinoma, distal cholangiocarcinoma and hilar/perihilar cholangiocarcinoma patients (p = 0.003, p = 0.004 and p < 0.001, respectively, Figure 1B-1D). Here, MRPL27 is linked to intrahepatic cholangiocarcinoma.