Moreover, patients in the severe cohort displayed a higher prevalence of neutrophil percentages > 70%, neutrophil counts > 6.3 × 109/L, lymphocyte percentages < 20%, lymphocyte counts < 1.0 × 109/L, platelet < 100 × 109/L, CRP > 10 mg/L than those in the moderate group, indicating that these parameters might be risk factors associated with COVID-19 severity in the general population. The gene discussed is CRP; the disease is COVID-19.