Eventually, we found that the uptake of 2-NBDLG was abolished by phloretin [18], an aglycone of natural polyphenol phlorizin and a broad-spectrum inhibitor against membrane transport including GLUTs/water channels [19, 20], implying that 2-NBDLG enters the tumor cells through non-GLUT/non-SGLT pathways [4]. Here, SLC2A1 is linked to neoplasm.