At univariate analysis, hyperlipidemia (odds ratio (OR) 4.620, 95% confidence interval (CI) 2.441–8.855; p = 0.001), hypertension (OR 2.200, 95% CI 1.181–4.100; p = 0.013), diabetes mellitus (OR 2.636, 95% CI 1.391–4.997; p = 0.003), CRP (OR 1.059, 95% CI 1.016–1.104; p = 0.007), low density lipoprotein (OR 1.011, 95% CI 1.002–1.020; p = 0.016), and nondipper hypertensions (OR 2.986, 95% CI 1.591–5.604; p = 0.001) were independent risk factors of progression in patients with CAD progressions (Table 3). This evidence concerns the gene CRP and hypertensive disorder.