qPCR analysis revealed that expression of brain natriuretic peptide (Bnp), a common marker for pathological cardiac remodelling, was increased in MI infarct and border regions compared to remote regions and sham hearts in both genotpyes (Fig. 2C); however, when comparing Bnp expression in each respective region of PMCA4−/− and WT MI hearts no differences were observed. Here, NPPB is linked to myocardial infarction.