EYS was also the most prevalent causative gene in the Japanese population studied by Maeda et al.29, implicated in 21 out of 33 AR-RP patients (63.6%), whereas in our population EYS was mutated in 5.5% of the families with “a priori” AR-RP diagnosis, being the fourth most frequent gene, after USH2A, CRB1 and ABCA4. However, the order of the causative genes in AR-RP changes after reviewing the clinical data of ABCA4 related IRD patients, since they were mostly reclassified as NON-RP, downgrading EYS as the third most common gene in AR-RP in our population. Here, ABCA4 is linked to retinitis pigmentosa 1.