TCGA data analysis was performed for the clinical significance of our microarray analysis results showing a reverse relation between the expression of βArr1 and some of the cell cycle genes, This analysis showed that the expression level of CDC45, BUB1, CCNB1, and CCNB2 genes was consistently upregulated and that of βArr1 was downregulated in breast tumours compared to normal tissue samples. The gene discussed is BUB1; the disease is breast neoplasm.