To examine if this correlation is also found in human cancer cells, a panel of 20 human cancer-derived cell lines (17 lung, 2 colon, and 1 cervix) were analyzed for the constitutive expression of mRNA encoding SDC1 and CASP4 (CASP4 and CASP5 are the human equivalent of CASP11 in mice) (Fig. 1A–C). Here, SDC1 is linked to cancer.