DKC1 and neoplasm: Metastatic lesions (Figure 4A) had significantly higher dyskerin immunoscores compared with their matched primary tumours (p = 0.003, Figure 4B), whereas ECs at advanced clinical stages (FIGO stages III&IV) had significantly lower dyskerin immunoscores compared with those at early stages (FIGO stages I&II, p = 0.04, Figure 4C).