On the other hand, in another clinical trial, 8 weeks supplementation using a VSL#3 probiotic capsule containing eight strains of lactic acid bacteria among 82 GDM women at 16 weeks of gestation significantly lowered insulin levels (16.6 ± 5.9 vs. 22.3 ± 4.9 μIU/mL, p = 0.04) and lowered HOMA-IR (3.7 ± 1.5 vs. 4.9 ± 1.2 μIU/mL, p = 0.03). This evidence concerns the gene INS and gestational diabetes.