KRAS and non-small cell lung carcinoma: By contrast, short-term lysine deprivation did not alter the survival of EGFR wild-type NSCLC cells, including NCI-H441 (KRAS-mutant), NCI-H838, and two isogenic cell lines (NCI-H838-KRASG12V and NCI-H838-KRASG12D) (Figure 1E; blue and brown bars) (Figure S1).