The comparison of SNCA transcript expression levels between both groups and controls revealed that the expression of SNCAtv1 and SNCAtv2, but not of SNCAtv3, was significantly higher in PD patients who presented first symptoms before the age of 70 years in comparison with both PD patients who debuted at 70 years or later, and controls (Figure 5d–f). Here, SNCA is linked to Parkinson disease.