In addition, 524 DMRs might be putative targets of Dnmt3b’s CA because they are hypermethylated in MYC;Dnmt3b+/+ lymphomas but not in MYC;Dnmt3bΔ/Δ or MYC;Dnmt3bCI/CI MTCLs that lack CA (Fig. 8D). This evidence concerns the gene DNMT3B and lymphoma.