The Benefits of Stroke Treatment Delivered Using a Mobile Stroke Unit Compared to Standard Management by Emergency Medical Services (BEST-MSU) study (NCT02190500) is a cluster randomized (by weeks) multicenter comparative effectiveness clinical trial that began in May 2014 and was on schedule to complete enrollment of the target number of tPA eligible patients by May 31, 2020 [1]. This evidence concerns the gene PLAT and stroke disorder.