IL6 and von Willebrand disease (hereditary or acquired): A recently published study by Govorov et al. determined the levels of sICAM-1 and IL-6 as part of a study of the effects of the menstrual cycle on the clotting and immune system of female vWD patients.18 Also in this study, higher levels of sICAM-1 and IL-6 were measured in patients with vWD compared to healthy women.18