Fibrosis is presumed to progress through enhanced stimulation of the TGF‐β pathway by transglutaminase type 2 (TG2), which promotes collagen I‐IV expression in the nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB) [37, 38, 39, 40]. The gene discussed is TGM2; the disease is fibrosis.