However, the fact that (i) the NeuroX variants are not evenly distributed across the PRKN locus (accounts for four misclassified samples) and that (ii) we were looking for CNVs as small as a single exon may have resulted in our approach missing or inaccurately calling CNVs in our large cohort comprising predominantly of late-onset PD cases. The gene discussed is PRKN; the disease is Parkinson disease.