IL10 and myalgic encephalomeyelitis/chronic fatigue syndrome: In addition to this, LPS can also modulate the production of the anti-inflammatory cytokine IL-10 (Saraiva and O’Garra 2010; van den Bosch et al. 2014) and measuring LPS-induced IL-10 response has been shown to be a sensitive marker for disturbed glucocorticoid regulation at least in patients with chronic fatigue syndrome (Visser et al. 2001).