In the analyses of oncogenic gene sets, we found six gene sets (SINGH KRAS Dependency Signature, CAMP UP.V1 UP, MYC UP.V1 UP, RB P107 DN.V1 UP, E2F1 UP.V1 UP and CSR LATE UP.V1 UP) associated with lung adenocarcinoma (Fig. 1B). The gene discussed is E2F1; the disease is lung adenocarcinoma.