Previous studies also suggested that compared with persons who never had asthma, asthmatic patients had elevated has inflammatory biomarkers such as C-reactive protein, interleukin-1β, tumor necrosis factor-alpha, interleukin-6, interleukin-8, and fibrinogen which could increase progress of atherogenesis and then lead to the occurrence of CVD events24,26. Here, TNF is linked to asthma.