For example, Hao et al. explored 10 genes (COL1A1, COL3A1, COL1A2, COL5A2, FN1, THBS1, COL5A1, SPARC, COL18A1 and COL11A1) as potential biomarkers and therapeutic targets for GC, through analysis data from the Gene Expression Omnibus (GEO) database4. The gene discussed is FN1; the disease is gastric cancer.