Moreover, the rs79327197 of HLA-DOA was related to survival rate, and it had higher mortality frequency in patients with minor allele, in which the allele with higher frequency in ALL or AML population was defined as a major allele, and the lower was minor allele (minor allele = G-allele; p = 0.008, OR = 0.217, 95% CI 0.065–0.720). This evidence concerns the gene HLA-DOA and acute lymphoblastic leukemia.