TRIM27 and graft versus host disease: For the donor-recipient pairs group, only the rs209130 of TRIM27 gene was related to the risk of GVHD grade 3–4 (p = 0.036), in which the matched gene polymorphism of rs209130 in donor-recipient pairs had a lower probability for getting grade3-4 GVHD than those who were unmatched (OR = 0.333, 95% CI 0.117–0.946).