NLRP3 and astrocytoma (excluding glioblastoma): Our transcriptomic data of U87MG cells 12 h after LPS stimulation and the TCGA RNASeq dataset of astrocytoma showed upregulation of genes related to inflammasome and ripoptosome pathways, namely MYD88, NLRP3, RIPK1 and RIPK3, and also SRF, JUN and IL1B, the downstream regulated genes.