A number were secreted by both ND-DF and T2DM-DF, including CCL2, CXCL1, MIF, SERPINE1/PAI-1, chemokine C-X-C motif ligand 12/ stromal cell-derived factor 1 (CXCL12/SDF-1), interleukin-6 (IL-6) and interleukin-8 (IL-8). This evidence concerns the gene CXCL1 and type 2 diabetes mellitus.