LYPD3 and breast cancer: Gruet et al. [51] described that LYPD3 mRNA expression levels were low in normal tissues, but there is a significant (P < 0.001) over-expression of LYPD3 in several malignant tissues (breast cancer, cervical squamous cell carcinoma and endocervical adenocarcinoma, lung adenocarcinoma, lung squamous cell carcinoma, pancreatic adenocarcinoma, testicular germ cell tumors and thymoma).