Gruet et al. [51] described that LYPD3 mRNA expression levels were low in normal tissues, but there is a significant (P < 0.001) over-expression of LYPD3 in several malignant tissues (breast cancer, cervical squamous cell carcinoma and endocervical adenocarcinoma, lung adenocarcinoma, lung squamous cell carcinoma, pancreatic adenocarcinoma, testicular germ cell tumors and thymoma). Here, LYPD3 is linked to lung adenocarcinoma.