At 1 month postoperatively, the positive rates of Ki-67 in the PJAC group and ACC group were 88.9 ± 0.2% and 28.3 ± 3.6%, respectively, and the difference was statistically significant (P< 0.05); the positive rates of Lin28 in the two groups were 34.6 ± 3.3% and 7.6 ± 1.4%, respectively (P < 0.05). This evidence concerns the gene LIN28A and adrenal cortex carcinoma.