At 3 months, the positive rates of Ki-67 in the PJAC group and ACC group were 53.6 ± 6.9% and 1.97 ± 0.3%, respectively (P< 0.05); the positive rates of Lin28 in the two groups were 86.6 ± 3.3% and 1.4 ± 0.3% , respectively (P < 0.01) (Figs. 1, 2, 3, and 4). The gene discussed is LIN28A; the disease is adrenal cortex carcinoma.