SLC7A5 and cancer: In the case of 10BPA, Nomoto et al. reported that poly(vinyl alcohol) (PVA)-10BPA reversible boronate esters in aqueous solution (PVA-10BPA) are internalized by cancer cells through LAT1-mediated endocytosis and then localize to endo−/lysosomes, enhancing cellular uptake and slowing untoward efflux.