KRAS and carcinoma: Lesions with mutations in KMTC2, which is commonly mutated with K-ras (part of the adenoma-carcinoma sequence and frequently mutated in TSAs) could be predicted by the abundance of Ruminococcus, which has been linked to IBD and CRC.48 Another study found that SSPs with dysplasia, but not without dysplasia or adenomas, had characteristic Clostridium perfringens infection.