IL6 and COVID-19: The activity of anakinra against COVID-19 is also phase 3 tested in combination therapies with Janus kinases (JAKs) inhibiting ruxolitinib (Incyte Corp in the US, Novartis rest of the world) (NCT04424056, EudraCT2020-001754-21) and with IL-6/receptor-axis interfering agents siltuximab (Janssen Pharmaceutica Beerse, Belgium) and tocilizumab (Hoffmann-La Roche, Basel, Switzerland) (NCT04330638).