In addition, after stimulation with phorbol 12-myristate 13-acetate and ionomycin, TNF-α and IFN-γ production by CD3+ T cells is decreased in DBA compared with healthy subjects and other inherited BMF syndromes, as well as TNF-α-producing CD14+ monocytes, while no alterations are reported in SDS [118]. The gene discussed is TNF; the disease is Diamond-Blackfan anemia.