In suggesting the in vivo role of muscular sclerostin on bone tissue, the authors are aware of the need to confirm the role of muscular sclerostin after the end of the somatic growth before proposing the validation of this protein as a therapeutic target for the treatment of bone processes directly linked to the pathological condition or indirectly, due to a muscular weakness, such as the condition of muscular dystrophy, neuronal atrophy, or cachexia. Here, SOST is linked to muscular dystrophy.