Cancer patients who participated in exercise had increased immune cell activity, such as CD3+ T lymphocytes, including CD4+ and CD8+, αβ T cells, γδ T cells, CD3−/CD16+/56+ NK cells and CD19+ B cells [93] and decreased insulin-like growth factors [94] and cytokines [95], which are probable causes of carcinogenesis. The gene discussed is CD8A; the disease is cancer.