IL6 and hepatocellular carcinoma: A prospective case-control study within the European Prospective Investigation into Cancer and Nutrition, showed that higher circulating concentrations of IL-6, C-reactive protein (CRP), C peptide, non-high molecular weight (HMW) adiponectin, and glutamate dehydrogenase were significantly associated with higher risk of HCC, independent on established liver cancer risk factors and high BMI.