CD4 and B-cell chronic lymphocytic leukemia: We found that in CLL cells, the pri-miR-181b2 and pri-miR-181a were controlled by exogenously activated CD4+T cells, both allogenic (p = 0.0007 and p = 0.0017 respectively, Wilcoxon test) (Figure 2A,B) and autologous (p = 0.0186 and p = 0.0029 respectively, Wilcoxon test) (Figure 2D,E).