BDNF and early-onset generalized limb-onset dystonia: Indeed, there is premature long-term potentiation (LTP) with increased levels of pro-brain-derived neurotrophic factor (BDNF) and BDNF and the accumulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic (AMPA) receptors in striatal spiny neurons of DYT1 dystonia model mice [29].