Since TLR7 and IFNα are intimately linked to lupus pathogenesis [35–38], we next wanted to expand on prior results in the 2,6,10,14-tetramethylpentadecane (TMPD, also known as pristane) elicited murine model of lupus [22, 39]. Here, TLR7 is linked to systemic lupus erythematosus.