Clinical investigations of drugs targeting the ACE2/Ang‐(1‐7)/MasR axis have proven that ARB drugs like azilsartan and statins like atorvastatin can delay the progression of diabetic cardiomyopathy by increasing the expression levels of ACE2 and Ang‐(1‐7) combined with ACEI or DIZE and neprilysin inhibition therapy to provide better heart protection.78, 79, 80, 81. This evidence concerns the gene ACE2 and diabetic cardiomyopathy.