Kaplan-Meier curves suggested that patients with high expression of FAM83A-AS1 exhibited a similar overall survival time with those with low FAM83A-AS1 levels (Fig. 1E), whereas ROC analysis showed that FAM83A-AS1 gained high accuracy in distinguishing ESCC (Fig. 1D). This evidence concerns the gene SACK1A and esophageal squamous cell carcinoma.