Since the expression of α-sma is commonly used to identify activated mesenchymal cells at the sites of desmoplastic cancer stroma, we believe that CTRP6 expression may also have an inhibitory effect on cancer stromal fibrosis in gastric cancer, which is consistent with reports of its expression in post infarct cardiac fibrosis 7, dermal fibrosis 8, and renal fibrosis 9. Here, ACTA1 is linked to renal fibrosis.