Dysfunction of the endothelial cells is an important contributor to the pathobiology of atherosclerosis, and the increased secretion of adhesion molecule such as ICAM-1 and VCAM-1 in endothelial cells facilitates the macrophage adhesion to endothelial cells (Gimbrone and García-Cardeña, 2016). Here, VCAM1 is linked to atherosclerosis.