Few recent studies of in vivo RNAi screen and in vivo/in vitro breast cancer cells have implicated SALL1 as a tumor suppressor in breast cancer by inhibiting cancer cell growth, proliferation, and cell-cycle arrest, through the Nucleosome Remodeling and Deacetylase network76 or by regulating CDH1, a contributor to epithelial-to-mesenchymal transition77. The gene discussed is SALL1; the disease is breast cancer.