For correlation between HIF-1α expression and tumor diameter of biopsy site (diameter was the average of long and short diameter) in various groups, Pearson’s correlation analysis showed no significant correlation (all P > 0.05, and all R2 < 0.3 except R2 = 0.469 of EGFR sensitive mutation group, Table 6). The gene discussed is EGFR; the disease is neoplasm.