Furthermore, large-scale recruitment of neutrophils, macrophages, and dendritic cells, along with CD54 upregulation on day 5 PI, controlled the fungal infection on day 2 PI, suggesting that that days 2 and 5 PI reflect the inflammatory peak in the lungs upon intravenous injection and that numerous fungi are recognized by TLR-2 and TLR-4. The gene discussed is TLR2; the disease is fungal infectious disease.