Of these 8 variants, (a) 7 were observed in the groups with obesity, including 5 synonymous variants in MT-ND4L (15 individuals), MT-ND6 (14 individuals), MT-CO2 (11 individuals), MT-ND5 (7 individuals), and MT-ND2 (7 individuals) genes, as well as 2 non-coding variants in MT-TP (12 individuals) and MT-TF (7 individuals) genes; (b) 1 was observed in the group without obesity, namely, a synonymous variant in the MT-ND1 gene (4 individuals). The gene discussed is TF; the disease is obesity due to melanocortin 4 receptor deficiency.