We prioritize the following candidate epilepsy genes, which are found in the epilepsy-focused modules of both the larger multiplex network and WES network: ANK2, CACNA1E, CACNA2D3, GRIA2. Another candidate epilepsy gene is DLG4, which is in epilepsy focused module of the WES network and autism-focused module of the larger phenotype network. Here, CACNA2D3 is linked to epilepsy.