Although in our previous studies we separately measured intracellular biomarkers in various cell types (lymphocytes, neutrophils) by flow cytometry, in this “start-up survivin in sepsis” study we only wanted to compare the early-onset antiapoptotic response of survivin to the cumulative extracellular and intracellular apoptotic induction of key caspases-3 and -9 in sepsis. The gene discussed is BIRC5; the disease is Sepsis.